New Gene Linked to Greater Risk of Brain & Ovarian Cancers

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Photo by Miguel Á. Padriñán on

New Gene Linked to Greater Risk of

Brain & Ovarian Cancers 

Genetic changes and variants linked to the development of brain and ovarian cancers have been discovered in two new studies. This significant development offers researchers the chance to understand more about how these cancers develop and how they may one day be treated or even prevented.

The two studies scanned the genomes of tens of thousand of individuals with and without these forms of cancer and revealed 13 new gene mutations linked to increased risk of glioma — the most common form of brain cancer — and 12 new gene variants that increase the risk of developing ovarian cancer.
One of the genetic changes discovered increases risk of brain cancer by as much as a third, with the rest by at least 15%.
Prior to the new study, 23 gene variants were already known to be linked to an increased risk of ovarian cancer, said Kuchenbaecker. This study identified an additional 12. The findings might also one day help people with a family history become better informed about their risk of developing a brain tumor so they can be aware of any signs of the disease.
“We urgently need to find new ways to tackle hard-to-treat cancers like brain tumors. Finding new genetic changes linked to brain tumors could give us important new clues about how and why these cancers develop,” said Dr. Catherine Pickworth, Cancer Research UK’s science information officer.
“The next steps will [be] finding out if any of these clues help to develop effective treatments for people with brain tumors.”



Join us for the seventh annual Cheryl Diamond NYC 5K SCHLEP: Breast & Ovarian Cancer Run / Walk on Sunday, June 4th, 2017 at Battery Park, NYC.

The NYC 5K SCHLEP raises global awareness for BRCA genetic screening for breast & ovarian cancer, supports global research studies on breast and ovarian cancer cures, and BRCA mutation carriers, and benefits the BRCA Multidisciplinary Clinic at Israel’s Rabin Medical Center, the premier hospital in the Middle East.

To register your team, please visit or call the American Friends of Rabin Medical Center office at 212-279-2522 or email



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